While traditional treatments like creams and facials can provide benefits, there’s a new wave of regenerative skincare that harnesses the body’s own healing power to truly rejuvenate the skin. As a dermatology nurse practitioner in a medical spa, I see how these treatments can transform a patient’s skin, giving them long-lasting, natural results. Throughout this blog we will explore how each treatment works, how they complement one another, and how they can rejuvenate the skin at a cellular level.
What Is Regenerative Skincare and How Does It Work?
Regenerative skincare is all about stimulating the body’s natural healing processes to improve skin health and appearance. Rather than relying solely on topical creams or fillers, regenerative treatments use the body’s own cells, growth factors, and natural substances to repair and renew the skin from the inside out.
These treatments work on a cellular level, boosting collagen production, enhancing elasticity, improving skin tone, and addressing various concerns like fine lines, wrinkles, acne scars, and loss of volume.
Now, let’s break down some of the most popular regenerative skincare treatments we offer here at NuIQ Wellness Lounge and Med Spa.
Laser Skin Resurfacing Treatments – MOXI® and HALO® in Cleveland
How This Treatment Works
MOXI is a gentle, non-ablative fractional laser designed for early skin rejuvenation, targeting sun damage, uneven tone, and texture with minimal downtime — ideal for younger skin or maintenance. HALO is a hybrid fractional laser that combines ablative and non-ablative wavelengths to deeply resurface the skin, improving wrinkles, scars, and elasticity in a single treatment with more intensive results.
Benefits of This Regenerative Skincare Treatment
- Reduces fine lines and wrinkles
- Fades sun damage, age spots, and acne scars
- Improves skin texture and tone
PRF Treatment – Platelet-Rich Fibrin for Skin Rejuvenation
How This Treatment Works
Platelet-Rich Fibrin (PRF) is a next-generation version of PRP (platelet-rich plasma), but more natural and potent. PRF contains a fibrin matrix, growth factors, and stem cells for sustained release and better regeneration.
Benefits of This Regenerative Skincare Treatment
- Stimulates long-term collagen production
- Treats under-eye hollows, fine lines, and skin laxity
- Can be injected or microneedled into the skin
PDGF – Platelet-Derived Growth Factor for Healing and Renewal
How This Treatment Works
Platelet-Derived Growth Factor (PDGF) is a powerful regenerative protein naturally found in the body and is one of the key growth factors present in PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin). It plays a critical role in stimulating cell growth, repairing damaged tissue, and forming new blood vessels, making it essential for skin regeneration.
PDGF by Arriessence is a topical bioengineered growth factor serum that delivers this regenerative power without the need for a blood draw. It’s specifically designed to support and enhance the skin’s healing process after advanced aesthetic treatments.
When to Use PDGF in Skin Treatments
- Post-laser treatments (e.g., MOXI®, HALO®, CO2)
- Microneedling
- A regenerative injection for pyriform or undereyes
Benefits of This Regenerative Skincare Treatment
- Accelerates wound healing
- Improves texture, tightness, and elasticity
- Stimulates fibroblasts = more collagen
Microneedling in Cleveland – With or Without PDGF/PRF
How This Treatment Works
A procedure that uses tiny needles to create controlled micro-injuries in the skin, triggering a healing response. You can enhance your procedure by adding on PDGF or PRF.
Benefits of This Regenerative Skincare Treatment
- Reduces acne scars, fine lines, large pores
- Boosts skin firmness and glow
- Improves product absorption
Sculptra Injections for Collagen and Volume Restoration
How This Treatment Works
Sculptra (Poly-L-Lactic Acid) is an injectable biostimulator—not a filler—that stimulates your body to produce its own collagen over time.
Top Uses for Sculptra in Aesthetic Treatments
- Volume loss (cheeks, temples)
- Skin laxity
- Deep lines and wrinkles
Benefits of This Regenerative Skincare Treatment
- Results build gradually and last 2+ years
- Creates natural-looking, long-term volume
- Improves overall skin thickness and texture
Radiesse – Collagen-Stimulating Filler for Firming and Contour
How This Treatment Works
Radiesse (Calcium Hydroxylapatite) is an injectable dermal filler and collagen stimulator composed of calcium-based microspheres suspended in gel.
Top Uses for Sculptra in Aesthetic Treatments
- Volume restoration
- Skin tightening (especially in the neck, jawline, hands)
- Hyperdiluted for biostimulation rather than volume
Benefits of This Regenerative Skincare Treatment
- Immediate lift plus long-term collagen growth
- Smooths wrinkles and enhances structure
- Excellent for “crepey” skin when diluted
(plated)™ Skin Science – Medical-Grade Topical Regenerative Skincare
How This Treatment Works
(plated)™ Skin Science is a medical-grade skincare line that uses lab-grown exosomes and stabilized growth factors, including PDGF, EGF, and TGF-β (no blood draw needed).
Benefits of This Regenerative Skincare Treatment
- Accelerates healing after treatments (like microneedling or laser)
- Improves tone, texture, and elasticity
- Ideal for aging, sensitive, or post-procedure skin
Why (plated)™ Skin Science Is a Breakthrough in Skincare
- Uses stabilized growth factors for at-home regenerative skincare
- Scientifically formulated with high potency
How to Choose the Right Regenerative Skincare Treatment
| Treatment | Primary Action | Best For |
|---|---|---|
| Laser Therapy | Resurfacing + collagen stimulation | Scars, pigmentation, texture |
| PRF | Natural collagen + healing | Under-eye, fine lines, crepey skin |
| PDGF | Growth + repair factor | In PRP/PRF, topical healing |
| Microneedling | Collagen induction | Scars, pores, wrinkles |
| Sculptra | Deep collagen stimulation | Volume loss, long-term firmness |
| Radiesse | Filler + collagen stimulator | Volume, skin tightening |
| Plated Skin Care | Topical growth factors | Post-procedure healing, daily rejuvenation |
